Recent progress in photoacoustic imaging technology
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摘要:光声成像技术是生物医学领域中新兴的无损检测技术,具有对比度高、分辨率好、穿透能力强等优点。本文介绍了光声成像技术近年来的进展状况,主要涉及成像探测方式的改进、成像速度的加快、成像分辨率的提高以及图像重构算法的发展等。以该项技术在现代临床诊断中的应用为例,描述了其在生物医学领域中应用范围的拓宽。最后,总结了该项技术现存的主要问题,指出多模式组合的成像方式,如光声与超声的组合,光声与OCT方式的组合是该项技术的发展趋势;另外,结合造影剂的分子光声成像技术也同样很有发展前景。Abstract:Photoacoustic Imaging Technology(PAT) with high contrast, excellent resolution and deep penetration is an emerging noninvasive detecting technology in biomedical applications. This paper introduces the latest progress in PAT, which contains the improvement of image detecting modes, increase of imaging speed, enhancement of imaging resolution and the modification of image reconstruction algorithm. By taking application of PAT to the clinical diagnosis as examples, it describes that the PAT applications have been expanded in biomedical fields. Finally, it overviews the shortcomings of the PAT, and points out that multi-mode combination will a developing trend of the PAT, such as combination of the photoacoustic imaging and the ultrasonic imaging or the photoacoustic imaging and the OCT. Moreover, the molecular PAT based on the contrast agent will also has a good prospect.
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